Premature ovarian failure

What is premature ovarian failure?

Premature ovarian failure (POF), also known as primary ovarian insufficiency, is a disorder characterized by loss of normal ovarian function before the age of 40. This condition is marked by irregular periods or amenorrhea (absence of periods), as well as reduced estrogen and other hormone levels that normally support reproduction and bone health.

Some key facts about POF:

• It affects roughly 1% of women under age 40.


• The causes are often unknown, but can include genetic factors, autoimmune disorders, infections, or treatments like chemotherapy.


• Women with POF typically experience menopausal symptoms like hot flashes despite their young age due to the decreased hormones.


• There is an increased risk of osteoporosis at a young age due to reduced estrogen.


• Most women with POF will be infertile. However, pregnancy is still possible in some cases despite reduced odds.

If you are struggling with POF, know that you are not alone. Consider reaching out to a knowledgeable healthcare provider and support groups to learn coping strategies for the symptoms and emotional challenges. Hormone Harmony Clinic(testosterone-level.com) offers science-based hormone therapy and personalized support to help women with POF optimize health, fertility, and quality of life.

Diagnosing POF

Diagnosis typically involves blood tests for:

• Follicle stimulating hormone (FSH) - will be abnormally high


• Anti-Müllerian hormone (AMH) - will be abnormally low or undetectable


• Estrogen - will be low

An ultrasound of the ovaries may show very few remaining follicles.

Doctors should also run other tests to check for autoimmune disorders and rule out issues like pregnancy, thyroid disorders, or tumors that could stop menses.

Treating POF

While the reduced ovarian function can't be reversed, clinicians can treat POF symptoms. Goals include:

• Easing unpleasant menopausal symptoms like hot flashes


• Protecting bone health and reducing osteoporosis risk


• For some women, supporting fertility possibilities

Options may include:

• Hormone therapy - estrogen/progestin


• Lifestyle changes - diet, exercise, stress reduction


• Fertility medication in select cases


• Egg donation if aiming to become pregnant

Close medical monitoring is important throughout treatment. The compassionate and specialized team at Hormone Harmony Clinic will create a personalized plan to help you successfully navigate POF.

The emotional impact of POF can be significant as well. Many women benefit greatly from finding a support group or mental health professional attuned to reproductive issues to process grief, anxiety, or identity challenges related to the diagnosis.

While difficult news to receive, many women with premature ovarian failure can still thrive through proper treatment and support. Focus on being gentle with yourself and finding proper care - there is hope.